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Title of Journal: Int J Colorectal Dis

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Abbravation: International Journal of Colorectal Disease

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Springer-Verlag

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DOI

10.1016/j.apcata.2010.01.003

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1432-1262

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Longterm results of botulinum toxin for the treat

Authors: A Arroyo F Perez P Serrano F Candela R Calpena
Publish Date: 2004/10/30
Volume: 20, Issue: 3, Pages: 267-271
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Abstract

No major complications were found initial incontinence at the 2month review 6 spontaneously reversed at 6 months There was a tendency of progressive recurrence over time with an overall healing after 3 years of 47 We found a group of patients with clinical symptoms longer than 12 months and presence of a sentinel pile before treatment and manometric factors persistently elevated mean resting pressure percentage of time with slow waves and number of patients or percentage of time with ultra slow waves after treatment associated with a higher recurrence of anal fissuresSince it avoids the greater risk of incontinence associated with surgical sphincterotomy we recommend the use of botulinum toxin as the first therapeutic approach for patients with chronic anal fissure and risk factors for incontinence despite the higher rate of recurrence associated with this treatment In patients with factors related to recurrence reinjection with higher doses of botulinum toxin or complementary medical–surgical treatment should be considered

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