Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Int J Colorectal Dis

Search In Journal Title:

Abbravation: International Journal of Colorectal Disease

Search In Journal Abbravation:

Publisher

Springer Berlin Heidelberg

Search In Publisher:

DOI

10.1016/0004-6981(78)90378-5

Search In DOI:

ISSN

1432-1262

Search In ISSN:
Search In Title Of Papers:

Longterm outcome of extralevator abdominoperineal

Authors: Sigmar Stelzner Gunter Hellmich Anja Sims Thomas Kittner Eric Puffer Joerg Zimmer Dorothea Bleyl Helmut Witzigmann
Publish Date: 2016/09/09
Volume: 31, Issue: 10, Pages: 1729-1737
PDF Link

Abstract

Extralevator abdominoperineal excision ELAPE was introduced to improve outcomes for lowlying locally advanced rectal cancers LARC not amenable to sphincter preserving procedures This study investigates prospectively outcomes of patients operated on with ELAPE compared with a similar cohort of patients operated on with conventional APEAfter the exclusion of patients without neoadjuvant therapy inhospital mortality and incomplete metastatectomy we identified 72 consecutive patients who had undergone either conventional APE n = 36 or ELAPE n = 36 for LARC ≤6 cm from the anal verge The primary outcome measure was local recurrence at 5 years and secondary outcome measures were causespecific and overall survivalMedian distance from the anal verge was significantly lower in the ELAPE group 2 vs 4 cm p = 0029 Inadvertent bowel perforation could be completely avoided in the ELAPE group but amounted to 167  in the conventional APE group p = 0025 Cumulative local recurrence rate at 5 years was 182  in the APE group compared to 59  in the ELAPE group p = 0153 Local recurrence without distant metastases occurred in 155  in the APE group but was not observed in the ELAPE group p = 0039 We did not detect significant differences in causespecific nor in overall survival

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Current perioperative practice in rectal surgery in Austria and Germany
  2. Shortcomings in colonic stenting to palliate large bowel obstruction from extracolonic malignancies
  3. Inflammatory bowel disease-associated colorectal cancer: proctocolectomy and mucosectomy do not necessarily eliminate pouch-related cancer incidences
  4. A high lymph node yield in colon cancer is associated with age, tumour stage, tumour sub-site and priority of surgery. Results from a prospective national cohort study
  5. Dietary restrictions for acute diverticulitis: evidence-based or expert opinion?
  6. Long-term results of botulinum toxin for the treatment of chronic anal fissure: prospective clinical and manometric study
  7. Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFα, improves health-related quality of life in patients with moderate to severe Crohn’s disease
  8. Impact of preoperative targeted therapy on postoperative complications after resection of colorectal liver metastases
  9. Spatiotemporal pattern analysis of transcription factor 4 in the developing anorectum of the rat embryo with anorectal malformations
  10. A new diagnostic scoring system to differentiate Hirschsprung’s disease from Hirschsprung’s disease-allied disorders in patients with suspected intestinal dysganglionosis
  11. A systematic review and meta-analysis of adjuvant chemotherapy after neoadjuvant treatment and surgery for rectal cancer
  12. Impact of fat obesity on laparoscopic total mesorectal excision: more reliable indicator than body mass index
  13. Occurrence of adenomas in the pouch and small intestine of FAP patients after proctocolectomy with ileoanal pouch construction
  14. Clinical and instrumental parameters in patients with constipation and incontinence: their potential implications in the functional aspects of these disorders
  15. Colonoscopy as a useful tool in determining the transition zone in transanal endorectal pull-through in Hirschsprung’s disease
  16. Risk of advanced metachronous colorectal adenoma during long-term follow-up
  17. Overall survival after resection for colon cancer in a national cohort study was adversely affected by TNM stage, lymph node ratio, gender, and old age
  18. L -arginine and glycine supplementation in the repair of the irradiated colonic wall of rats
  19. A observational study of the efficacy and safety of capecitabine versus bolus infusional 5-fluorouracil in pre-operative chemoradiotherapy for locally advanced rectal cancer
  20. “Pseudocarcinomatosis peritoneii”: extensive intraperitoneal endometriosis mimic carcinomatosis in morphology—a case report and a survey of the literature
  21. Long-term results of laparoscopy-assisted radical right hemicolectomy with D3 lymphadenectomy: clinical analysis with 177 cases
  22. Permanent sacral nerve modulation for fecal incontinence and associated urinary disturbances
  23. Adenocarcinoma in the ileal pouch: early detection and potential role of fecal DNA methylated markers in surveillance
  24. Analysis of the factors related to the decision of restoring intestinal continuity after Hartmann’s procedure
  25. Sacral neuromodulation for fecal incontinence and constipation in adult patients with anorectal malformation—a feasibility study in patients with or without sacral dysgenesis
  26. Tetrandrine ameliorates dextran-sulfate-sodium-induced colitis in mice through inhibition of nuclear factor -κB activation
  27. Colonic irrigation for defecation disorders after dynamic graciloplasty
  28. Local excision of low rectal cancer treated by chemoradiotherapy: is it safe for all patients with suspicion of complete tumor response?
  29. In reply to Tin et al.
  30. Rectal cancer surgery: volume–outcome analysis
  31. Signet-ring cell carcinoma of the rectum and synchronous renal cell carcinoma in a young man
  32. Long-term follow-up and development of diverticulitis in patients diagnosed with diverticulosis of the colon
  33. Fecal transplant is as effective and safe in immunocompromised as non-immunocompromised patients for Clostridium difficile
  34. DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study
  35. Adequacy of lymph node yield and staging in rectal cancer should not be determined based on a minimum number of lymph nodes evaluated
  36. Failure of a meta-analysis on the role of elective surgery for left colonic diverticulitis in young patients
  37. Long-segment hypoplasia of the left hemicolon 4 months after sigmoid resection and loop transversostomy in a patient with intestinal endometriosis
  38. Invited commentary on “Werkgartner G. et al.: laparoscopic versus open appendectomy for complicated appendicitis in high risk patients”
  39. Long-term survival after resection of extrahepatic recurrence of hepatocellular carcinoma at the right colon
  40. Association of NQO1 Pro187Ser polymorphism with the risks for colorectal cancer and colorectal adenoma: a meta-analysis
  41. Caspase-3 activity, response to chemotherapy and clinical outcome in patients with colon cancer
  42. Erratum to: Successful implantation of autologous muscle-derived stem cells in treatment of faecal incontinence due to external sphincter rupture
  43. Experiences of two centers of bariatric surgery in the treatment of intragastrale band migration after gastric banding—the importance of the German multicenter observational study for quality assurance in obesity surgery 2005 and 2006
  44. Infliximab versus cyclosporine as rescue therapy in acute severe steroid-refractory ulcerative colitis: a systematic review and meta-analysis
  45. Haemorrhoids are related to changes of cell function in mucosa and submucosa
  46. Urinary and sexual dysfunction rates and risk factors following rectal cancer surgery
  47. Anal inspection and digital rectal examination compared to anorectal physiology tests and endoanal ultrasonography in evaluating fecal incontinence
  48. ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery
  49. Prophylactic stoma mesh did not prevent parastomal hernias
  50. Level of arterial ligation in total mesorectal excision (TME): an anatomical study
  51. Gender differences in the trend of colorectal cancer incidence in Singapore, 1968–2002
  52. Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis
  53. Appendectomy, tonsillectomy, and risk of inflammatory bowel disease: a case control study in Iran
  54. A rare case of intra-cardiac metastasis from an appendiceal carcinoid tumour without liver metastases
  55. Prognostic value of carcinoembryonic antigen level in rectal cancer treated with neoadjuvant chemoradiotherapy
  56. Short-course radiotherapy with delayed surgery in unfit locally advanced rectal cancer patients
  57. Skeletal muscle disorders associated with inflammatory bowel diseases: occurrence of myositis in a patient with ulcerative colitis and Hashimoto's thyroiditis—case report and review of the literature
Search Result: