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Title of Journal: Int J Colorectal Dis

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Abbravation: International Journal of Colorectal Disease

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Springer-Verlag

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DOI

10.1007/s15002-013-0062-z

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1432-1262

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ErbB family immunohistochemical expression in colo

Authors: Glauco Baiocchi Ademar Lopes Renata A Coudry Benedito M Rossi Fernando A Soares Samuel Aguiar Gustavo C Guimarães Fabio O Ferreira Wilson T Nakagawa
Publish Date: 2009/04/24
Volume: 24, Issue: 9, Pages: 1059-
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Abstract

The immunohistochemical expression was considered positive for EGFR ErbB2 ErbB3 ErbB4 membrane and ErbB4 cytoplasmic in respectively 578 83 697 11 and 193 of patients ErbB3 negative expression was associated with lymphovascular invasion EGFR ErbB2 and cytoplasmic ErbB4 expression was not associated with prognosis Membranous positive ErbB4 expression was an independent prognostic factor for recurrence ErbB3 negative expression was an independent prognostic factor for recurrence and survival in the multivariate analysis

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