Authors: Marco Lupattelli Valentina Lancellotta Giampaolo Montesi Vittorio Bini Danilo Castellani Lorenzo Falcinelli Isabella Palumbo Cynthia Aristei
Publish Date: 2015/11/19
Volume: 31, Issue: 6, Pages: 1233-1234
Abstract
It is well known that preoperative radiotherapy RT alone or in combination with chemotherapy CRT is the standard of care for patients with locally advanced rectal cancer with both schedules being equivalent in terms of local recurrence and survival Shortcourse radiotherapy SCRT according to a hypofractionated schedule 25 Gy in 5 fractions followed by immediate surgery is extensively used in resectable disease as it offers the advantages of shorter treatment time lower costs and less acute toxicity On the other hand it is not recommended when disease downsizing/downstaging and sphincter saving procedure are required because the interval between the end of RT and surgery is too short for rectal cancer clearance 1
Keywords: