Authors: Jakob Lykke Per Jess Ole Roikjær On behalf of the Danish Colorectal Cancer Group
Publish Date: 2016/05/24
Volume: 31, Issue: 7, Pages: 1299-1305
Abstract
An analysis was carried out of the LNY in a nationwide Danish cohort treated by curative resection of stage I–III colon cancer in the period 2003–2011 The association between a LNY ≥ 12 and age sex body mass index open vs laparoscopic surgery acute vs elective surgery pT stage tumour subsite and year of diagnosis was analysedA total of 13766 patients were eligible for the analysis In total 714 of the patients had a LNY ≥ 12 In multivariate analysis age pT stage tumour subsite and priority of surgery were independently associated with the probability of a LNY ≥ 12 Odds ratios ORs were as follows age 65 1 65–75 0685 confidence interval CI 0586–0800 75 0517 CI 0439–0609 T1 1 T2 2750 CI 2168–3487 T3 6016 CI 4879–7418 T4 6317 CI 4950–8063 right colon 1 left colon 0568 0511–0633 elective surgery 1 acute surgery 0748 CI 0625–0894 Moreover year of diagnosis was associated with the probability of a LNY ≥ 12 OR 1480 CI 1445–1516 for each increasing year in the study periodA LNY ≥ 12 is significantly associated with age pT stage tumour subsite and priority of surgery A significant increase in the LNY over the period of the study was observed probably reflecting the effect of national programmes initiated by the Danish Colorectal Cancer Group
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