Authors: Amar Mandalia Angela Ward William Tauxe Colleen S Kraft Tanvi Dhere
Publish Date: 2015/09/26
Volume: 31, Issue: 5, Pages: 1059-1060
Abstract
Clostridium difficile infection CDI is a leading cause of nosocomial infection and is associated with significant morbidity and mortality Immunocompromised IC patients are particularly at higher risk Recurrence rates of up to 60 have been reported after the third episode despite treatment with antibiotics Recent published reports of fecal microbiota transplantation FMT in the IC population have shed light that the procedure proves to be effective and safe No studies that compare the efficacy and adverse event rate of FMT between IC and nonIC patients currently exist The aim of our study is to compare the response and serious adverse event SAE rates of FMT for recurrent or refractory CDI RCDI between IC patients and nonIC patientsDr Amar Mandalia assisted in study concept design acquisition of data drafting of manuscript and critical revision of the manuscript for important intellectual content Ms Angela Ward and Mr William Tauxe assisted in acquisition of data Dr Colleen Kraft lent technical and material support and was involved in critical review of the manuscript for important intellectual content Dr Tanvi Dhere was involved in study concept and design acquisition of data analysis and interpretation of data critical revision of the manuscript for important intellectual content statistical analysis and overall study supervision
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