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Title of Journal: Chin Sci Bull

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Abbravation: Chinese Science Bulletin

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Science China Press

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DOI

10.1007/s40278-015-9669-y

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1861-9541

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Recent advances in brown adipose tissue biology

Authors: Yanyan Shen Xiaomeng Liu Meng Dong Jun Lin Qianwei Zhao HyuekJong Lee Wanzhu Jin
Publish Date: 2014/05/17
Volume: 59, Issue: 31, Pages: 4030-4040
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Abstract

In mammals white adipose tissue WAT store energy whereas brown adipose tissue BAT burns energy As a thermogenic organ BAT can help maintain body temperature during cold exposure Owing to its important roles in energy metabolism and regulating triacylglycerol levels BAT has received great attention in treating obesity and its related diseases Recent studies have suggested that BAT may secrete factors—batokines—to regulate wholebody energy metabolism In this review we summarize the recent advances in the formation and function of BAT as well as molecules that regulate the activity of BAT and beige fatThis work was supported by the One Hundred Talents Program of the Chinese Academy of Sciences and the Ministry of Science and Technology of China 2012CBA01301 and 2012CB944701 the National Natural Science Foundation of China 81370951 31171131 and the Key Research Program of the Chinese Academy of Sciences KJZDEWL013 to Wanzhu Jin

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