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Title of Journal: Intensive Care Med

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Abbravation: Intensive Care Medicine

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Springer-Verlag

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DOI

10.1007/s11589-004-0018-0

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1432-1238

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Cognitive and perceived health status in patient w

Authors: Nicolino Ambrosino Gisella Bruletti Valnea Scala Roberto Porta Michele Vitacca
Publish Date: 2001/12/04
Volume: 28, Issue: 2, Pages: 170-177
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Abstract

Objective To evaluate the perceived health and cognitive status in survivors of chronic obstructive pulmonary disease COPD exacerbations requiring mechanical ventilation Design and setting Prospective controlled cohort study in a respiratory intermediate intensive care unit Patients Sixtythree COPD patients at their first episode of acute on chronic respiratory failure requiring mechanical ventilation controls were 34 consecutive stable COPD patients on longterm oxygen therapy with no previous ICU admission Measurements and results Perceived health and cognitive status by means of the Nottingham Health Profile NHP and the Mini Mental State MMS respectively at discharge and 3 and 6 months thereafter At discharge patients showed significantly worse mean values than controls in MMS and in all NHP dimensions except pain The MMS score was below 24 the threshold level of cognitive impairment in 43 patients of the study group but only 3 of controls p=0006 Six months after discharge patients showed NHP and MMS values similar to those of controls and the proportion of patients with a MMS score below 24 had significantly decreased to 17 a value not significantly different from that in controls 5 Conclusions COPD patients surviving their first episode of acute on chronic respiratory failure requiring mechanical ventilation suffer worsen perceived health status and cognitive function which 6 months after discharge may improve to levels similar to those in stable COPD patients on longterm oxygen therapy with no previous ICU admission

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