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Title of Journal: Intensive Care Med

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Abbravation: Intensive Care Medicine

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Springer-Verlag

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DOI

10.1007/bf03300395

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1432-1238

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Ionic dialysance a new valid parameter for quanti

Authors: Christophe Ridel David Osman Lucile Mercadal Nadia Anguel Thierry Petitclerc Christian Richard Christophe Vinsonneau
Publish Date: 2007/01/18
Volume: 33, Issue: 3, Pages: 460-465
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Abstract

Several studies have reported a close relationship between an increased dose of dialysis and survival in patients treated for acute renal failure Unfortunately the quantification of dialysis in critically ill patients based on the urea nitrogen formula Kt/V is not applicable Ionic dialysance is a new parameter calculated in real time from the dialysate conductivity and correlated with the effective urea clearance in chronic hemodialysis patients The aim of our study was to evaluate ionic dialysance in the quantification of dialysis in critically ill patients with acute renal failureUsing the first dialysis session of each patient we compared the delivered dose of dialysis based on ionic dialysance measurement KtID with the wellaccepted gold standard method based on fractional dialysate sampling Ktdialysate The data were analyzed using linear regression and Bland–Altman analysisThirtyone intermittent hemodialysis sessions were performed in 31 critically ill patients mean age 58 ± 12 years SAPS II score 56 ± 10 We found a close correlation between Ktdialysate and KtID Ktdialysate = 363 ± 114 l KtID = 384 ± 118 r = 096 with excellent limits of agreement –22 l 64 l

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