Authors: Nikolaus A Haas Jan Kemke Ingram SchulzeNeick Peter E Lange
Publish Date: 2004/09/09
Volume: 30, Issue: 11, Pages: 2102-2109
Abstract
Right heart catheterisation for the measurement of cardiac output pulmonary artery pressure central venous pressure and pulmonary capillary wedge pressure arterial cannulation for measurement of arterial pressures and ionised magnesium levels calculation of pulmonary and systemic vascular resistance before and after induction of acute pulmonary microembolism and without or with the administration of magnesium 05 10 20 mmol/kg bolus and 1 mmol/kg bolus followed by 1 mmol/kg per h continuous infusionThe bolus administration of increasing doses of magnesium 05 10 20 mmol/kg was associated with an increase in ionised serum magnesium levels and a dosedependent decrease of mean pulmonary arterial pressure an increase of cardiac output and a decrease of pulmonary vascular resistance This effect was sustained after bolus administration 1 mmol/kg followed by a continuous infusion of magnesium 1 mmol/kg per h
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