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Title of Journal: Intensive Care Med

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Abbravation: Intensive Care Medicine

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Springer-Verlag

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DOI

10.1007/bf01618428

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1432-1238

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Monitoring brain tissue oxygen tension in brainin

Authors: Luca Longhi Francesca Pagan Valerio Valeriani Sandra Magnoni Elisa R Zanier Valeria Conte Vincenzo Branca Nino Stocchetti
Publish Date: 2007/09/01
Volume: 33, Issue: 12, Pages: 2136-2142
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Abstract

Mean PtiO2 in the pericontusional tissue was 197 ± 21 mmHg and was lower than PtiO2 in normalappearing tissue 255 ± 15 mmHg p  005 despite a greater cerebral perfusion pressure CPP 737 ± 23 mmHg vs 674 ± 14 mmHg p  005 We observed both in perifocal tissue and in normalappearing tissue episodes of brain hypoxia PtiO2  20 mmHg for at least 10 min whose median duration was longer in perifocal tissue than in normalappearing tissue 51 vs 34 of monitoring time p  001 In perifocal tissue we observed a progressive PtiO2 increase from pathologic to normal values p  001Multiple episodes of brain hypoxia occurred over the first 5 days following severe TBI PtiO2 was lower in pericontusional tissue than in normalappearing tissue In pericontusional tissue a progressive increase of PtiO2 from pathologic to normal values was observed over time suggestive of an improvement at microcirculatory level

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