Authors: Alberto Luini Marisel Aguilar Giovanna Gatti Roberta Fasani Edoardo Botteri Jack Antonio Diaz Brito Patrick Maisonneuve Anna Rita Vento Giuseppe Viale
Publish Date: 2006/09/29
Volume: 101, Issue: 3, Pages: 349-353
Abstract
Metaplastic carcinoma of the breast is a rare form of breast cancer and has an uncertain prognostic significance The purpose of the present study was to compare the clinical course and prognosis between this type of tumor and poorly differentiated ductal carcinomaWe analyzed 37 cases of metaplastic carcinoma of the breast treated at our institution European Institute of Oncology in Milan Italy between 1997 and 2004 comparing them with 72 cases control group of poorly differentiated ductal carcinoma All 109 patients had negative receptors and were G3 at final histology The control cases were matched according to year of surgery pT pT1 vs pT2/3/4 and pN absent vs presentOf the 37 patients eleven died from disease progression eight developed metastatic disease and two experienced local recurrence In the control group 72 patients we observed three deaths due to disease progression 13 distant metastases and two local recurrences
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