Authors: Paula H B BoltonMaggs Victoria S L Kok
Publish Date: 2010/03/23
Volume: 89, Issue: 1, Pages: 61-65
Abstract
Chronic ITP immune thrombocytopenic purpura now defined as duration of more than 12 months is not always associated with significant bleeding problems so that most children and adults can be managed expectantly with no medication unless surgery accidents or other pathology mandate it A cutoff platelet count of 30 × 109/l divides a group with no increased mortality from those whose risk is greater and in whom medication is usually appropriate There is increasing recognition of longterm morbidity and mortality associated with immune suppression induced by medication and more recently new concerns have arisen about the longterm vascular complications of splenectomy A more conservative approach to medication is warranted in many patients with chronic ITP
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