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Title of Journal: Ann Hematol

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Abbravation: Annals of Hematology

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Springer Berlin Heidelberg

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DOI

10.1002/prac.19773190220

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ISSN

1432-0584

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Remissions of different quality following rituxima

Authors: Linus Angenendt Andrea Kerkhoff Stefanie Wiebe JanHenrik Mikesch Annika Rudat Fabian Wötzel Christian Wenning Christoph Schliemann Torsten Kessler Michael Schäfers Eva Wardelmann Matthias Stelljes Wolfgang E Berdel
Publish Date: 2015/03/21
Volume: 94, Issue: 7, Pages: 1241-1243
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Abstract

Multicentric Castleman’s disease MCD is a rare lymphoproliferative disorder characterized by hypercytokinemia undulating signs of systemic inflammation generalized lymphadenopathy hepatosplenomegaly and in severe cases vascular leak syndrome VLS organ failure and death 1 It is categorized into HHV8positive MCD HMCD including HIV patients and idiopathic MCD iMCD Therapeutic monoclonal antibodies are the mainstay of treatment Whereas the antiCD20 antibody rituximab is preferentially advocated for HMCD 2 3 the IL6 disrupting antibodies tocilizumab and siltuximab are for iMCD 4 We report the first case to our knowledge of a patient with severe iMCD responding with repeated longlasting complete remissions CR to rituximab monotherapy and after failure a complete remission to allogeneic stem cell transplantation alloSCT

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  2. Prophylactic intravenous immunoglobulin during autologous haemopoietic stem cell transplantation for multiple myeloma is not associated with reduced infectious complications
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  4. A systematic review and meta-analysis of rituximab-based immunochemotherapy for subtypes of diffuse large B cell lymphoma
  5. Therapeutic implication of BAL in patients with neutropenia
  6. Effect of altered iron metabolism on markers of haem biosynthesis and intestinal iron absorption in mice
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  8. Patients with diffuse large B cell lymphoma in partial response or stable disease after first-line R-CHOP: the prognostic value of the absolute lymphocyte count and impact of autologous stem cell transplantation
  9. Lung injury in a leukemia patient during mobilization of peripheral blood stem cells using granulocyte colony-stimulating factor alone
  10. Primary MALT lymphoma of the urinary bladder in the background of interstitial cystitis
  11. Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial
  12. Epidemiological profile of hemoglobinopathies in the Mauritanian population
  13. Efficacy and safety of deferasirox in myelodysplastic syndromes
  14. Haemoglobin Hokusetsu [β52 (D3)] Asp→Gly in German families associated with inclusion body
  15. Suggestion of response evaluation criteria in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML)
  16. Porcine antilymphocyte globulin (p-ALG) plus cyclosporine A (CsA) treatment in acquired severe aplastic anemia: a retrospective multicenter analysis
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