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Title of Journal: J Nanopart Res

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Abbravation: Journal of Nanoparticle Research

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Springer Netherlands

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DOI

10.1016/1040-0486(92)90001-x

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1572-896X

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Probing the fungicidal property of CdS quantum dot

Authors: Muthu Manikandan HuiFen Wu
Publish Date: 2013/06/14
Volume: 15, Issue: 7, Pages: 1728-
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Abstract

For the first time we report the successful application of inhouse synthesized CdS quantum dots QDs with particle sizes between 1 and 7 nm exhibiting excellent fungicidal activity based on the interactions with Saccharomyces cerevisiae and Candida utilis The growth curves and the growth rates of both fungi were established in the presence of three varying concentrations of CdS QDs It was observed that the CdS QDs were highly inhibitory even at the lowest concentration of 10 mg/L used in this study while the untreated control cells followed a normal growth pattern in the cases of both Saccharomyces and Candida MALDIMS was applied to substantiate the observations obtained by direct cell count method It was observed that the trend observed in the case of Saccharomyces and Candida was wellrepresented in the MALDIMS spectra This study proposes a mechanism for the first time based on MALDIMS results that the CdS QDs interact with the extracellular polymeric substances EPS and remove small molecules from EPS layer on the other hand it was observed that CdS QDs at all concentrations lead to enrichment of protein signals in MALDIMS We have substantiated these results by quantifying the EPS in the control and treated cells and also using TEM to further confirm the results

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