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Title of Journal: Eur J Pediatr

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Abbravation: European Journal of Pediatrics

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Springer-Verlag

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10.1016/0379-6779(94)03152-v

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1432-1076

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Is procalcitonin a good marker of renal lesion in

Authors: David Tuerlinckx Thierry Vander Borght Youri Glupczynski Laurence Galanti Véronique Roelants Bruno Krug Georges de Bilderling Eddy Bodart
Publish Date: 2005/07/16
Volume: 164, Issue: 10, Pages: 651-652
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Abstract

Four recent prospective studies have suggested that procalcitonin PCT a polypeptide produced by the macrophagemonocyte system during severe bacterial infection might be more specific than leukocyte count or Creactive protein CRP in predicting acute renal involvement during an episode of febrile urinary tract infection UTI 1 2 3 5 The aim of our prospective study was to confirm such findingsBlood samples were collected at admission for the determination of white blood cells WBCs and neutrophil counts CRP value normal value 5 mg/l and PCT level Lumitest PCT Brahms Diagnostica normal value 05 ng/ml in all 1month to 15yearold children admitted to our hospital between January 1999 and December 2003 with a cultureproven first episode of febrile UTI Acute renal involvement was assessed by 99mTcdimercaptosuccinic acid DMSA scintigraphy performed within 72 h of admission

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