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Title of Journal: Eur J Pediatr

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Abbravation: European Journal of Pediatrics

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Springer-Verlag

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DOI

10.1002/nme.1419

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1432-1076

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Pressureinduced angioedema associated with endotr

Authors: Çağlar Ödek Tanıl Kendirli Funda Çipe Banu Katlan Figen Doğu
Publish Date: 2012/04/21
Volume: 171, Issue: 10, Pages: 1573-1575
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Abstract

Pressureinduced urticaria is a nonimmunoglobulin Emediated type of urticaria Some patients only have angioedema and the term pressureinduced angioedema PIA is more appropriate for them PIA has not previously been reported in association with endotracheal tube Here we describe two patients who developed PIA after endotracheal intubation There were no histories of angioedema drug and food allergy in both patients Tests for specific aeroallergens and latex were negative Serum total immunoglobulin E and C4 levels were in normal ranges Antihistamines and intravenous steroid therapy were ineffective Angioedema regressed with intravenous epinephrine infusion and did not relapse after extubation Conclusion We suggest that endotracheal tubes can cause PIA Epinephrine therapy should be used early at treatment especially in the patients who are at great risk for lifethreatening airway problems

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