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Title of Journal: Eur J Pediatr

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Abbravation: European Journal of Pediatrics

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Springer Berlin Heidelberg

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DOI

10.1016/0023-9690(80)90008-9

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1432-1076

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Proportional assist versus assist control ventilat

Authors: Sandeep Shetty Prashanth Bhat Ann Hickey Janet L Peacock Anthony D Milner Anne Greenough
Publish Date: 2015/07/31
Volume: 175, Issue: 1, Pages: 57-61
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Abstract

During proportional assist ventilation PAV the applied pressure is servocontrolled based on continuous input from the infant’s breathing In addition elastic and resistive unloading can be employed to compensate for the abnormalities in the infant’s lung mechanics The aim of this study was to test the hypothesis that in very prematurely born infants remaining ventilated beyond the first week PAV compared to assist control ventilation ACV would be associated with superior oxygenation A randomised crossover study was undertaken Infants were studied for 4 hours each on PAV and ACV in random order at the end of each 4h period the oxygenation index OI was calculated Eight infants median gestational age of 25 range 24–33 weeks were studied at a median of 19 range 10–105 days It had been intended to study 18 infants but as all the infants had superior oxygenation on PAV p = 00039 the study was terminated after recruitment of eight infants The median inspired oxygen concentration p = 0049 mean airway pressure p = 0012 and OI p = 0012 were all lower on PAV

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