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Title of Journal: Eur J Pediatr

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Abbravation: European Journal of Pediatrics

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Springer Berlin Heidelberg

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DOI

10.1016/0584-8539(93)80024-5

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1432-1076

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Changes in the perfusion waveform of the internal

Authors: Toshifumi Ikeda Takasuke Amizuka Yuya Ito Ryosuke Mikami Koji Matsuo Naoto Kawamura Shintaro Fusagawa
Publish Date: 2014/08/30
Volume: 174, Issue: 3, Pages: 331-338
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Abstract

This prospective observational study aimed to investigate the association between changes in the Doppler perfusion waveform of the internal cerebral vein and risk of intraventricular hemorrhage IVH in extremely lowbirthweight ELBW infants We evaluated the perfusion waveform of the internal cerebral vein every 8 h from immediately after birth to 144 h postbirth in 80 ELBW infants 1000 g in our hospital Fluctuations in the measured perfusion waveform were categorized into four patterns according to their increasing magnitude from grade 0 steady flow waveform to grade 3 the IVH rate was investigated Infants with grades 0–1 fluctuations of the perfusion waveform were classified as low grade n = 55 and those with grades 2–3 fluctuations were classified as high grade n = 25 The IVH rate was significantly higher in the highgrade group than the lowgrade group 28 vs 1  p  0001 The IVH group n = 8 showed a significantly greater rate of highgrade perfusion waveform than the nonIVH group n = 72 87 vs 25  p  0001 Conclusion Changes in the perfusion waveform of the internal cerebral vein during the acute management of ELBW infants may be associated with IVHInformed consent was obtained from the parents or legal guardians of each infant enrolled in the study The present study was approved by the appropriate ethics committee and has therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments

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