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Title of Journal: Eur J Pediatr

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Abbravation: European Journal of Pediatrics

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Springer-Verlag

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10.1007/978-3-211-75125-1_7

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1432-1076

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de Quervain thyroiditis in a young boy following h

Authors: Pontipa Engkakul Pat Mahachoklertwattana Preamrudee Poomthavorn
Publish Date: 2010/10/01
Volume: 170, Issue: 4, Pages: 527-529
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Abstract

de Quervain thyroiditis also known as subacute thyroiditis is a selflimited inflammatory disease of the thyroid gland It is extremely rare in children The hallmarks for diagnosis are painful thyroid enlargement elevated inflammatory markers and decreased uptake of the thyroid gland on thyroid scintigraphy Viral infection has been proposed to be associated with de Quervain thyroiditis Coxsackie virus has been reported to be one of the viruses associated with the disease To our knowledge childhood de Quervain thyroiditis associated with hand–foot–mouth disease caused by coxsackie infection has never been reported We report a 27yearold boy who presented with typical features of de Quervain thyroiditis following hand–foot–mouth disease caused by coxsackie B4 infection He had a brief thyrotoxic phase initially followed by transient hypothyroid phase and euthyroidism thereafter His thyroid scintigraphy showed a typical faint uptake at the diagnosis and an improvement of the thyroid scan and uptake was shown 8 weeks later He was treated with prednisolone and nearly complete resolution was documented within 2 months Careful evaluation of the patient led to the correct diagnosis and appropriate management

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