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Title of Journal: Arch Gynecol Obstet

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Abbravation: Archives of Gynecology and Obstetrics

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Springer-Verlag

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DOI

10.1006/bbrc.1994.1795

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1432-0711

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A randomized trial comparing a polyherbal pessary

Authors: Yamal Patel Sarala Gopalan Rashmi Bagga Meera Sharma Seema Chopra Sunil Sethi
Publish Date: 2008/01/31
Volume: 278, Issue: 4, Pages: 341-347
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Abstract

Most women with abnormal vaginal discharge have infection due to candida species bacterial vaginosis or trichomoniasis and often seek treatment without laboratory confirmation In this context a single agent effective against these infections would be usefulOverall 82 82/100 reported symptomatic relief 78 39/50 with Praneem and 86 43/50 with GinlacV Only 36 18/50 in each group had laboratoryconfirmed infection 18 18/100 candidosis 17 17/100 bacterial vaginosis 1 1/100 both none had trichomoniasis Among these symptomatic improvement was seen in 72 13/18 and laboratory cure in 78 14/18 with Praneem symptomatic improvement in 78 14/18 and laboratory cure in 78 14/18 with GinlacV Clinical or laboratory criteria could assess treatment efficacy equally Neither drug was efficacious in candidosis GinlacV was efficacious in bacterial vaginosis 100 and though Praneem showed a similar trend it was not statistically significant Vaginal irritation was more frequent with Praneem 16 vs 4 with GinlacV

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