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Title of Journal: Arch Gynecol Obstet

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Abbravation: Archives of Gynecology and Obstetrics

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Springer Berlin Heidelberg

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DOI

10.1002/adfm.201503366

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ISSN

1432-0711

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Indocyanine green fluorescence imaging in the preg

Authors: Iori Kisu Kouji Banno Megumi Yanokura Yuya Nogami Kiyoko Umene Kosuke Tsuji Kenta Masuda Arisa Ueki Yusuke Kobayashi Daisuke Aoki
Publish Date: 2013/05/31
Volume: 288, Issue: 6, Pages: 1309-1315
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Abstract

Uterine blood flow is required for the maintenance of uterine viability in pregnancy and delivery but it is unknown how many vessels are necessary for maintenance of uterine viability The objective of this study was to examine whether unilateral uterine vessels provide sufficient nutrition in pregnancy in a cynomolgus macaque and to evaluate hemodynamics of pregnant uterus by indocyanine green ICG fluorescence imagingPregnancy was maintained with the right uterine artery and vein An appropriatefordate infant was delivered by Cesarean section ICG fluorescence imaging showed that the uterine body was imaged from the right side to the center furthermore collateral circulation was present from the right uterine artery toward the left uterine artery with expanded blood flow to the left uterine bodyWe are grateful to Tomoharu Mine and Yuhei Shigeta of IMI Co Ltd for their technical assistance and to Hirohito Kato Nobuyoshi Yamashita Yoshiro Nishida Kotaro Hanaki Ryuichi Katagiri Tomoko Shimonosono and Shuzo Koyama of Shin Nippon Biomedical Laboratories for experimental support This study was supported by the Strategic Research Foundation Grantaided Project for Private Universities from Ministry of Education Culture Sport Science and Technology Japan MEXT Graduate School Doctoral Student GrantinAid Program 2012 Keio University GrantinAid for Encouragement of Young Medical Scientists Kanzawa Medical Research Foundation Akaeda Medical Research Foundation the Japan Society for the Promotion of Science JSPS through a GrantinAid for Scientific Research KAKENHI a GrantinAid for Scientific Research B 22390313 a GrantinAid for Scientific Research C 22591866 and a GrantinAid for Young Scientists B 21791573 and the Keio University Medical Science Fund through a Research Grant for Life Sciences and Medicine The funders had no role in study design data collection and analysis decision to publish or preparation of the manuscript

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