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Title of Journal: Arch Gynecol Obstet

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Abbravation: Archives of Gynecology and Obstetrics

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Springer-Verlag

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DOI

10.1002/bewi.200601220

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ISSN

1432-0711

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Specific secretory phase endometrial leukocytes of

Authors: Michael K Bohlmann Doerte W Luedders Thomas Strowitzki Michael von Wolff
Publish Date: 2009/07/15
Volume: 281, Issue: 6, Pages: 983-990
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Abstract

Biopsies of exactly dated secretory endometrium in 25 patients with idiopathicrepeated abortions and 10 control patients without a history of miscarriage were compared with respect to the concentrations of Thelper cells CD4 cytotoxic Tcells CD8 Bcells CD19 and uterine natural killer cells CD56 by immunohistochemistry and RNase protection assaysThis study suggests that the concentrations of specific endometrial leukocytes in a nonpregnant cycle are not associated with repeated pregnancy loss Thus the hypothesis of an altered endometrial immunity in patients with repeated miscarriages symbolized by persistently differing local immunecell concentrations has to be questioned

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