Authors: Masumeh Mobli Marzieh Qaraaty Gholamreza Amin Ismaeil Haririan Mannan Hajimahmoodi Roja Rahimi
Publish Date: 2015/01/31
Volume: 292, Issue: 1, Pages: 21-35
Abstract
Abnormal uterine bleeding AUB is one of the prevalent gynecological disorders that cause considerable morbidity and management of that plays an important role in protecting women’s health This review focuses on medicinal plants mentioned by Avicenna a great Iranian philosopher and physician AD 980–1037 in his book Canon for treatment of AUBMedicinal plants mentioned in Canon for treatment of AUB were elicited and searched in electronic databases including PubMed Scopus Google Scholar and Cochrane library to find studies that confirmed their efficacy Data were collected for the years 1980–2014The findings included 23 plants belonging to 18 families Scientific findings have revealed that these plants control AUB through four mechanisms of action including inhibition of inflammatory process inhibition of prostaglandins production antiproliferative activity on human cervical cancer cells HeLa and estrogenic activity All of the plants exhibited antiinflammatory activity in vitro and/or in vivo Cuscuta chinensis and Portulaca oleracea exhibited estrogenic activity Boswellia carteri Lens culinaris Myrtus communis Polygonum aviculare Pistacia lentiscus and Punica granatum have revealed inhibitory activity on biosynthesis of prostaglandins Some of the mentioned plants including Ceratonia siliqua Cuscuta chinensis Cuscuta epithymum Cydonia oblonga Paeonia sp Portulaca oleracea Solanum nigrum Rumex acetosa and Onopordum acanthium have shown antiproliferative activity on HeLa cells
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