Authors: Yuanyuan Qi Liling Qian Bo Sun Chao Chen Yun Cao
Publish Date: 2010/04/30
Volume: 59, Issue: 10, Pages: 889-895
Abstract
Circulating CD34+ cells were identified by flow cytometry in 41 RDS in comparison with 20 preterm and 14 term controls without diffuse lung diseases Plasma concentrations of vascular endothelial growth factor stromal cellderived factor1 SDF1 and granulocyte–macrophage colonystimulating factor were determined by immunochemical assaysThe number of CD34+ cells was significantly higher in RDS 256–174 cells/μl than in the preterm controls 151–100 cells/μl P 005 RDS survivors had higher level of CD34+ cells than nonsurvivors P 005 and low CD34+ cell level in RDS was correlated with prolonged duration of ventilation r = −0396 P 005 Likewise the CD34+ cell level was inversely associated with Score for Neonatal Acute Physiology Perinatal Extension II r = −0473 P 001 in RDS Plasma SDF1 concentration was significantly higher in RDS than in the preterm controls P 001 and was correlated with the level of CD34+ cells r = 0305 P 001
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