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Title of Journal: Chem Nat Compd

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Abbravation: Chemistry of Natural Compounds

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Springer US

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DOI

10.1007/s10600-010-9735-x

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1573-8388

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Indole alkaloids from the roots of Emphasis Type=

Authors: DongDong Sun Weiwei Dong Xiang Li HanQing Zhang
Publish Date: 2010/11/10
Volume: 46, Issue: 5, Pages: 763-766
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Abstract

A new indole alkaloid 1 together with four known indole alkaloids 2–5 was isolated from the 95 EtOH extract of the traditional Chinese medicinal plant Isatis indigotica Alkaloids 2–5 were found in the plant for the first time Their structures were elucidated as 3hydroxy3acetonitrile4hydroxy2indolone 1 1methoxy3indoleacetonitrile 2 3indoleacetic acid 3 3indolealdehyde 4 and 1methoxy3indolecarbaldehyde 5 on the basis of spectroscopic data Their antiHSV effects in vitro were evaluated by plaque reduction assayThe authors would like to acknowledge the assistance of Prof HanQing Zhang Institute of Botany Jiangsu Province and the Chinese Academy of Sciences This work was cofinanced by grants from the Jiangsu Province administration of traditional chinese medicine basic research projects HZ0704407KJD

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