Authors: ZengBao Wu Yang Liu ShanShan Tian Chen Wen
Publish Date: 2014/01/12
Volume: 49, Issue: 6, Pages: 1162-1163
Abstract
Fraxinus rhynchophylla Hance belongs to the Oleaceae family and is widely distributed in China It is one of the sources of the traditional Chinese herbal drug “Qinpi” and has been used as an antiinflammatory agent for many years The traditional Chinese herbal drug “Qinpi” was reported to have diuretic antifebrile analgesic and antirheumatic activities 1 Coumarins lignans secoiridoid glucosides and other compounds have been isolated from plants of the genus Fraxinus 23 In order to find more bioactive compounds an investigation of the chemical constituents of Fraxinus rhynchophylla was carried outThe fresh stem barks of F rhynchophylla3 kg were cut into pieces and extracted with methanol three times under reflux The solvent was removed under reduced pressure to give a crude extract 100 g The crude extract was subjected to 200–300 mesh silica gel column chromatography eluting with a gradient of chloroform–methanol 201 to 11 to yield 20 fractions
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