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Title of Journal: Rheumatol Int

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Abbravation: Rheumatology International

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Springer-Verlag

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DOI

10.1002/jctb.5000545111

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1437-160X

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Clinical features of Behçets disease in patients

Authors: EM ElAgeb MH AlMaini AK AlShukaily Y AlFarsi ER Richens
Publish Date: 2001/12/18
Volume: 21, Issue: 5, Pages: 176-181
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Abstract

The prevalence of symptoms in 34 Omani patients with Behçets disease BD was recurrent oral ulceration 100 arthritis/arthralgia and genital ulceration 74 each folliculitis 64 neurological lesions 62 retinal vasculitis 30 iritis and hypopyon 26 gastrointestinal lesions 12 venous thrombosis and cardiovascular lesions 9 each and pleuropulmonary lesions and epididymitis 6 each Antiphospholipid APL antibodies both anticardiolipin ACAs and antiβ2 glycoprotein I aβ2GPIs were present in 11/34 32 of the BD patients and in 54/73 74 of Omani patients with systemic lupus erythematosus SLE χ2=212 P0001 In patients possessing APL antibodies there was no significant difference in mean antibody levels between BD and SLE patients IgM isotype antibodies in the absence of IgG were more prevalent in BD 5/11 than in SLE 10/54 patients χ2=38 P=005 The frequency of organ involvement was similar in patients with and without APL antibodies χ2=1226 P005 This study fails to demonstrate a pathognomonic role for APL antibodies in BD

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