Authors: Dirk Elewaut Filip Van den Bosch Gust Verbruggen Filip de Keyser Bert Vander Cruyssen Herman Mielants
Publish Date: 2008/09/26
Volume: 29, Issue: 3, Pages: 239-250
Abstract
Spondyloarthritides SpAs are a cluster of chronic inflammatory rheumatic diseases that typically involve inflammation of axial and peripheral joint or tendon and ligament insertions distinct radiographic changes and diverse extraarticular features Conventional treatments relieve the signs and symptoms but do not prevent disease progression TNFα inhibitors provide clinicians with the potential to treat the underlying pathology and to alter disease progression By targeting the underlying inflammatory mechanisms TNFα blockade can treat any extraarticular manifestations of SpA
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