Authors: Archambault F Poirier L Cleroux J Boileau’ G Lacourcière Y
Publish Date: 1995/04/01
Volume: 8, Issue: 4_Pt_2, Pages: 192A-192A
Abstract
F Archambault L Poirier J Cleroux G Boileau’ Y Lacourcière D27
COMPARATIVE EFFICACY OF HYDROCHLOROTHIAZIDE AND AMLODIPINE IN ELDERLY SUBJECTS WITH AMBULATORY HYPERTENSION American Journal of Hypertension Volume 8 Issue 4 Pt 2 April 1995 Page 192A https//doiorg/101016/089570619598088GRecent studies have advocated the use of lowdose diuretics as firstline treatment agents in elderly hypertensive patients However their results were based solely on blood pressure BP measured in the clinic The objective of this doubleblind study was to compare the effects of hydrochlorothiazide HCTZ and amlodipine AML in elderly patients with confirmed ambulatory hypertension After a 4week placebo washout period 42 25M 17F patients mean age 69 y with a sitting diastolic BP of 95–114 mm Hg in the clinic and daytime ambulatory BP of ≥ 90 mm Hg were randomized doubleblind to receive AML 5–10 mg n=21 or HCTZ 125–25 mg n=21 per day to achieve goal clinic diastolic BP of 90 mm Hg If diastolic BP remained ≥ 90 mm Hg after
Keywords: