Authors: Páll Dénes Katona Éva M Zrínyi Miklós Paragh György Zatik János Bereczki Dániel Fülesdi Béla
Publish Date: 2005/05/01
Volume: 18, Issue: S4, Pages: 113A-113A
Abstract
Dénes Páll Éva M Katona Miklós Zrínyi György Paragh János Zatik Dániel Bereczki Béla Fülesdi P298 Screening of adolescent hypertension and evaluation of target organ damages Results from the Debrecen hypertension study American Journal of Hypertension Volume 18 Issue S4 May 2005 Page 113A https//doiorg/101016/jamjhyper200503316We performed a crosssectional populationbased survey in Debrecen All high school attending youths a total sample of 10359 average age was 162±10 years participated in the study Following a 10 minute rest 3 repeated BP measurements were taken by a validated OMRON M4 devices Subjects completed a demographic and lifestyle survey as well The 50th 90th and 95th percentile value of the BP were defined by dividing the adolescent population into age gender and heightspecific subgroups In comparison with US guidelines in our sample the systolic BP of boys in the different subgroups was 6 to 11 mmHg higher while this difference was less marked for girls 1 to 5 mmHg There were no marked differences in diastolic BP With the help of a multiplex regression model we analyzed factors influencing BP At systolic BP gender β=0373 and BMIβ=0261 had a largest relative weight while age β=0043 fathers hypertension β=0042 and mothers hypertension β=038 had a smaller but also significant importance BMI β=0264 gender β=0097 age β=0052 fathers HTN β=0041 and mothers HTN β=0038 were predictive of diastolic BP Adjusted R2 was 0281 at systolic and 0181 at diastolic BP Systolic and/or diastolic BP exceeded the age gender and height adjusted 90th percentile of 1614 1584 adolescents Performing 2x3 extra measurements on this sample 234 of the subjects had confirmed HTN Target organ damage was observed in numerous cases left ventricular hypertrophy in 13 retinopathy in 12 and microalbuminuria in 10 of hypertensives IMT in the common carotid artery was higher in hypertensive adolescents means±SD 055±011 mm than in healthy control subjects 048±008 mm p0001 Similar to this a higher LVMI was measured in hypertensive 1027±305 g/m2 than in healthy teenagers 911±252 g/m2 p001 The screening of high blood pressure is important in adolescence also because of the prevalence and the target organ damages Early diagnosis of hypertension and followup may lead to the prevention of target organ damages
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