Authors: Ishikawa Joji Kario Kazuomi Hoshide Satoshi Morinari Masato Eguchi Kazuo Ishikawa Shizukiyo Shimada Kazuyuki
Publish Date: 2005/05/01
Volume: 18, Issue: S4, Pages: 261A-261A
Abstract
Joji Ishikawa Kazuomi Kario Satoshi Hoshide Masato Morinari Kazuo Eguchi Shizukiyo Ishikawa Kazuyuki Shimada P692 24hr ambulatory mean blood pressure vs pulse pressure as a predictor of silent cerebral infarcts in older Japanese hypertensives American Journal of Hypertension Volume 18 Issue S4 May 2005 Page 261A https//doiorg/101016/jamjhyper200503709SCI was detected in 257 subjects 50 and multiple SCI ≥2 SCI was detected in 102 subjects 198 Multiple SCI subjects had higher level of age diabetes clinic systolic BP 24hr ambulatory systolic and diastolic BP 24hr mBP and PP than the others In logistic regression after adjusting for confounding factors the odds ratios of multiple SCI for the second third and forth quartiles of 24hr mBP to the first were 142 95 confidence interval CI 652–3093 p=038 219 95 CI 1041–4615 p=004 and 442 95 CI 2185–9055 P0001 and those of 24hr PP were 149 95 CI 654–3400 p=034 354 95 CI 1647–7600 p=0001 318 95 CI 1480–6812 p=0003 When 24hr PP and 24hr mBP were entered into the same model only the odds ratios of the forth quartile of mBP to the first remained significant odds ratio 342 95 CI 133–881 p=001
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