Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Eur J Nutr

Search In Journal Title:

Abbravation: European Journal of Nutrition

Search In Journal Abbravation:

Publisher

Steinkopff-Verlag

Search In Publisher:

DOI

10.1016/0005-2736(75)90342-9

Search In DOI:

ISSN

1436-6215

Search In ISSN:
Search In Title Of Papers:

Effect of prenatal exposure to ethanol on postnat

Authors: Sonali Bhalla Safrun Mahmood Akhtar Mahmood
Publish Date: 2004/01/06
Volume: 43, Issue: 2, Pages: 109-115
PDF Link

Abstract

Alcohol consumption by pregnant animals and humans leads to general growth impairment in their offspring delayed growth and multiple birth defects collectively called “Fetal Alcohol Syndrome” In utero exposure of ethanol to rat pups causes damage to their developing intestinal epithelium which leads to impairment of nutrient assimilation and growth retardation during postnatal developmentTo determine the effect of prenatal exposure of ethanol on the postnatal development of rat intestinal Na+dependent and independent Dglucose transporter along with the amino acids glycine and Lleucine transporter activity at 4 8 14 20 and 30 days of postnatal age The changes in the expression levels of Na+dependent glucose transporter SGLT1 mRNA was assessed at different days of postnatal age in rat pupsWistar strain albino female rats were fed ethanol at a dose of 2 g/kg body weight/day orally by Ryle’s tube for one month before mating and during the entire period of gestation while the control females received isocaloric glucose Transport studies were performed using the everted intestine of 4 8 14 20 and 30 dayold control and ethanolexposed pups employing the tissue accumulation method The expression of SGLT1 mRNA at different days of postnatal age in control and ethanolexposed rat pups was determined using a Northern Blot analysisPrenatal exposure of ethanol to rat pups leads to a decrease in their body weight intestinal length and weight and reduces the uptake capacities of SGLT1 as well as energy dependent glycine and Lleucine transporters with respect to their agematched controls However the mRNA levels of SGLT1 remained unaltered in the ethanolexposed pups at all ages of postnatal development compared to their controlsThese findings suggest that in utero exposure to ethanol leads to a general delay in the postnatal development of the intestine of ethanolexposed rat pups affecting mainly the development of intestinal energy dependent Dglucose and amino acid glycine and Lleucine transporters

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Alcohol consumption and the risk of coronary heart disease in postmenopausal women with diabetes: Women’s Health Initiative Observational Study
  2. Replacement of glycaemic carbohydrates by inulin-type fructans from chicory (oligofructose, inulin) reduces the postprandial blood glucose and insulin response to foods: report of two double-blind, randomized, controlled trials
  3. Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the Generation R Study
  4. Effects of a new low dose soy protein/β-sitosterol association on plasma lipid levels and oxidation
  5. Modified apple polysaccharide prevents against tumorigenesis in a mouse model of colitis-associated colon cancer: role of galectin-3 and apoptosis in cancer prevention
  6. Genotoxic effect of bile acids on human normal and tumour colon cells and protection by dietary antioxidants and butyrate
  7. Gender difference on the association between dietary patterns and metabolic syndrome in Korean population
  8. MnSOD and CAT polymorphisms modulate the effect of the Mediterranean diet on breast cancer risk among Greek-Cypriot women
  9. DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism
  10. Functional foods/ingredients and dental caries
  11. Preventive rather than therapeutic treatment with high fiber diet attenuates clinical and inflammatory markers of acute and chronic DSS-induced colitis in mice
  12. The effect of clinical characteristics and dietary habits on the relationship between education status and 5-year incidence of cardiovascular disease: the ATTICA study
  13. Lycopene enhances UVA–induced DNA damage and expression of heme oxygenase–1 in cultured mouse embryo fibroblasts
  14. Maternal low-protein diet affects myostatin signaling and protein synthesis in skeletal muscle of offspring piglets at weaning stage
  15. Factors affecting the conversion of apple polyphenols to phenolic acids and fruit matrix to short-chain fatty acids by human faecal microbiota in vitro
  16. Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet
  17. Vitamin D status indicators in indigenous populations in East Africa
  18. Chronic undernutrition alters renal active Na + transport in young rats: potential hidden basis for pathophysiological alterations in adulthood?
  19. Iodine status in preschool children and evaluation of major dietary iodine sources: a German experience
  20. Zufuhr an Vitaminen und Mineralstoffen aus Nahrungsergänzungspräparaten in der MONICA-Querschnittsstudie 1994/95 der Studienregion Augsburg
  21. Mice fed fish oil diet and upregulation of brown adipose tissue thermogenic markers
  22. Health-promoting substances and heavy metal content in tomatoes grown with different farming techniques
  23. Solubility, uptake and biocompatibility of lutein and zeaxanthin delivered to cultured human retinal pigment epithelial cells in tween40 micelles
  24. Short-chain fructooligosaccharides, in spite of being fermented in the upper part of the large intestine, have anti-inflammatory activity in the TNBS model of colitis
  25. Vitamin D status in young Swedish women with anorexia nervosa during intensive weight gain therapy
  26. Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts
  27. Anticarcinogenic compounds of olive oil and related biomarkers
  28. Lactobacillus GG-fermented milk prevents DSS-induced colitis and regulates intestinal epithelial homeostasis through activation of epidermal growth factor receptor
  29. Einfluß unterschiedlich hoher Vitamin-E-Gaben an Mastschweine auf die Fleisch- und Speckqualität in Abhängigkeit von der Lagerung
  30. Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers
  31. Current micronutrient recommendations in Europe: towards understanding their differences and similarities
  32. Total fluid intake and its determinants: cross-sectional surveys among adults in 13 countries worldwide
  33. Adaptive response activated by dietary cis 9, trans 11 conjugated linoleic acid prevents distinct signs of gliadin-induced enteropathy in mice
  34. Adaptive response activated by dietary cis 9, trans 11 conjugated linoleic acid prevents distinct signs of gliadin-induced enteropathy in mice
  35. ‘Designer oils’ low in n-6:n-3 fatty acid ratio beneficially modifies cardiovascular risks in mice
  36. Bioactive peptides and proteins from foods: indication for health effects
  37. Body weight and energy homeostasis was not affected in C57BL/6 mice fed high whey protein or leucine-supplemented low-fat diets
  38. Minimising the population risk of micronutrient deficiency and over-consumption: a new approach using selenium as an example
  39. Coffee and caffeine intake and risk of endometriosis: a meta-analysis
Search Result: