Authors: Demosthenes B Panagiotakos Christos Pitsavos Christina Chrysohoou Konstantinos Vlismas Yannis Skoumas Konstantina Palliou Christodoulos Stefanadis
Publish Date: 2008/07/05
Volume: 47, Issue: 5, Pages: 258-
Abstract
From 2001 to 2002 1514 men and 1528 women 18 year without known CVD were enrolled In 2006 the 5year followup was performed 31 participants were lost to followup Development of fatal or nonfatal CVD coronary heart disease acute coronary syndromes stroke or other CVD was defined according to WHOICD10 criteria Education status was measured in years of school while baseline dietary habits were assessed through a semiquantitative foodfrequency questionnaire EPICGreek The MediterraneanDietScore was applied to assess overall adherence to this pattern using scores of 11 foodvariables and alcohol according to the principles of the MediterraneandietThe 5year incidence of CVD was 108 110 cases in men and 62 61 cases in women P 0001 32 16 of these events were fatal 21 in men People in the low education group had significantly higher prevalence of hypertension diabetes and dyslipidemias were more likely to be sedentary and smokers compared to high group Moreover compared to high people in low education group had less healthy dietary habits as assessed using the diet score P 0001 Multiadjusted analysis revealed that low education was positively associated with 5year incidence of CVD after adjusting for age and sex HR = 164 95CI 105–255 however this association lost its significance when clinical characteristics and dietary habits were taken into account HR = 131 95CI 063–274The ATTICA Study is funded by research grants from the Hellenic Society of Cardiology and the Hellenic Atherosclerosis Society The authors would like to thank the investigators of “ATTICA” study A Zeimbekis N Papaioannou E Tsetsekou L Papadimitriou N Massoura S Vellas A Katinioti physical examination M Toutouza data management M Kambaxis dietary assessment M Toutouza C Tselika and S Poulopoulou technical support
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