Authors: Cynthia VillarrealGarza Miriam RojasFlores Andrea CastroSánchez Antonio R Villa Luis GarcíaAceituno Eucario LeónRodríguez
Publish Date: 2010/06/02
Volume: 28, Issue: 4, Pages: 973-980
Abstract
The purpose of this study was to compare the outcome and resectability of patients with gastric cancer recurrence after curative surgery detected by followup endoscopy according to the presence or absence of symptoms All patients with gastric carcinoma who underwent a curative gastrectomy were retrospectively identified We analyzed outcome and survival in patients compliant with routine followup who presented symptomatic and asymptomatic recurrence Of the 119 resected patients 630 had a recurrence with an overall survival of 200 months Fourteen patients were asymptomatic when recurrence was detected whereas 61 patients were symptomatic Median time to recurrence was 160 m for both groups A local curative reresection was possible in 2/14 asymptomatic and 1/61 symptomatic Asymptomatic patients had a longer median postrecurrence survival time of 90 months compared with 20 months in the symptomatic patients p=0034 The median overall survival was greater in the asymptomatic vs symptomatic group 250 vs 200 months although this did not reach statistical significance The results from this study advocate that the presence or absence of symptoms is a good surrogate marker to assess biologic aggressiveness The value of routine followup endoscopy to permit a higher rate of reresection in asymptomatic patients remains to be establishedStudy conception and design VillarrealGarza LeónRodríguez Collection of data VillarrealGarza RojasFlores CastroSánchez Analysis and interpretation of data VillarrealGarza Villa LeónRodríguez Systematic review of literature and drafting of manuscript VillarrealGarza GarcíaAceituno Final approval of manuscript VillarrealGarza RojasFlores CastroSánchez Villa GarcíaAceituno LeónRodríguez
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