Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Endocrine

Search In Journal Title:

Abbravation: Endocrine

Search In Journal Abbravation:

Publisher

Springer US

Search In Publisher:

DOI

10.1007/bf00971632

Search In DOI:

ISSN

1559-0100

Search In ISSN:
Search In Title Of Papers:

Infectious diseases and immunological responses in

Authors: Viviane C Campos Mônica R Barrios Roberto Salvatori Roque Pacheco de Almeida Enaldo V de Melo Ana C S Nascimento Amélia Ribeiro de Jesus Manuel H AguiarOliveira
Publish Date: 2016/08/03
Volume: 54, Issue: 1, Pages: 182-190
PDF Link

Abstract

Growth hormone is important for the development and function of the immune system but there is controversy on whether growth hormone deficiency is associated to immune disorders A model of isolated growth hormone deficiency may clarify if the lack of growth hormone is associated with increased susceptibility to infections or with an altered responsiveness of the immune system We have studied the frequency of infectious diseases and the immune function in adults with congenital untreated isolated growth hormone deficiency In a crosssectional study 35 adults with isolated growth hormone deficiency due to a homozygous mutation in the growth hormone releasing hormone receptor gene and 31 controls were submitted to a clinical questionnaire physical examination serology for tripanosomiasis leishmaniasis HIV tetanus hepatitis B and C and serum total immunoglobulin G M E and A measurement The immune response was evaluated in a subset of these subjects by skin tests and response to vaccination for hepatitis B tetanus and bacillus CalmetteGuérin There was no difference between the groups in history of infectious diseases and baseline serology Isolated growth hormone deficiency subjects had lower total IgG but within normal range There was no difference in the response to any of the vaccinations or in the positivity to protein Purified Derived streptokinase or candidin Adult untreated isolated growth hormone deficiency does not cause an increased frequency of infectious diseases and does not alter serologic tests but is associated with lower total IgG levels without detectable clinical impactAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Molecular Features of Follicular Variant Papillary Carcinoma of Thyroid: Comparison of Areas With or Without Classical Nuclear Features
  2. Medical therapy: Options and uses
  3. The role of sex, adiposity, and gonadectomy in the regulation of irisin secretion
  4. The changing faces of corticotroph cell adenomas: the role of prohormone convertase 1/3
  5. Harmful effects of functional hypercortisolism: a working hypothesis
  6. Lifetime, untreated isolated GH deficiency due to a GH-releasing hormone receptor mutation has beneficial consequences on bone status in older individuals, and does not influence their abdominal aorta calcification
  7. Prognostic Significance of CD44 and Orthopedia Homeobox Protein (OTP) Expression in Pulmonary Carcinoid Tumours
  8. Vitamin D and diabetes mellitus
  9. Reference values for handgrip strength in young people of both sexes
  10. Reference values for handgrip strength in young people of both sexes
  11. WS1 gene mutation analysis of Wolfram syndrome in a Chinese patient and a systematic review of literatures
  12. True Mixed Medullary Papillary Carcinoma of the Thyroid: a Case Report with Low Blood Calcitonin Levels
  13. Chronic pediatric inflammatory diseases: Effects on bone
  14. Cardiovascular events in acromegaly: distinct role of Agatston and Framingham score in the 5-year prediction
  15. The association of adiposity with parathyroid hormone in healthy older adults
  16. Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain
  17. Study of the role of novel RF-amide neuropeptides in affecting growth hormone secretion in a representative non-human primate ( Macaca mulatta )
  18. Insulin-like growth factor I, growth hormone, and insulin sensitivity: the effects of a one-year cholecalciferol supplementation in middle-aged overweight and obese subjects
  19. Parathyroid Hemangioma: A Case Report in Proof of its Existence
  20. Thyroid Cancers with Benign-Looking Sonographic Features Have Different Lymph Node Metastatic Risk and Histologic Subtypes According to Nodule Size
  21. Blood glucose fluctuation accelerates renal injury involved to inhibit the AKT signaling pathway in diabetic rats
  22. The Cancer Genome Atlas Research Network: A Sight to Behold
  23. Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject
  24. Serum anti-mullerian hormone and all-cause mortality in men
  25. Bone mineral density and bone fracture in male patients receiving long-term suppressive levothyroxine treatment for differentiated thyroid carcinoma
  26. CLM29 and CLM24, pyrazolopyrimidine derivatives, have antitumoral activity in vitro in anaplastic thyroid cancer, with or without BRAF mutation
  27. Safety and efficacy of contraception—Why should the obese woman be any different?
  28. Cushingoid lipodystrophy can be prevented by thiazolidinediones
  29. Long non-coding RNA ENSMUST00000147869 protects mesangial cells from proliferation and fibrosis induced by diabetic nephropathy
  30. Envoi
  31. The exon 3 polymorphism of the growth hormone receptor is a severity-related factor for osteoporosis
  32. Cushing’s syndrome in type 2 diabetes patients with poor glycemic control
  33. Longitudinal associations between lifestyle and vitamin D: A general population study with repeated vitamin D measurements
  34. A 47, XXY patient and Xq21.31 duplication with features of Prader–Willi syndrome: results of array-based comparative genomic hybridization
  35. Exploring attitudes towards endocrine diseases in Greece
  36. Quality of life in the patients with central diabetes insipidus assessed by Nagasaki Diabetes Insipidus Questionnaire
  37. Primary Pituitary Lymphoma: A Histological, Immunohistochemical, and Ultrastructural Study with Literature Review
  38. PGE2 modulates the transcriptional activity of ERRa in prostate stromal cells
  39. Differential gene expression in ERα-positive and ERα-negative breast cancer cells upon leptin stimulation
  40. Regulatory T cells in type 1 diabetic patients with autoimmune chronic atrophic gastritis
  41. Extracellular vesicles as an emerging mechanism of cell-to-cell communication
  42. Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas
  43. Clinical characteristics as predictors of malignancy in patients with indeterminate thyroid cytology: a meta-analysis
  44. Interleukin-18 enhances glucose uptake in 3T3-L1 adipocytes
  45. A Novel Mutation (P236S) in the Succinate Dehydrogenase Subunit B Gene in a Japanese Patient with a Posterior Mediastinal Paraganglioma
  46. Coronary flow reserve after l -thyroxine therapy in Hashimoto’s thyroiditis patients with subclinical and overt hypothyroidism
  47. Comparative analysis of vaspin in pregnant women with and without gestational diabetes mellitus and healthy non-pregnant women
  48. Worsening of lipid metabolism after successful treatment of primary aldosteronism
  49. Serum ischemic modified albumin levels might not be a marker of oxidative stress in patients with hypothyroidism
  50. Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome
  51. Metabolic syndrome and associated chronic kidney diseases: Nutritional interventions
  52. The AIP (aryl hydrocarbon receptor-interacting protein) gene and its relation to the pathogenesis of pituitary adenomas
  53. Clinical vertebral fractures following denosumab discontinuation
  54. Role of insulin resistance in endothelial dysfunction
  55. Gender-specific associations between subclinical hypothyroidism and blood pressure in Chinese adults
  56. Signaling Pathways in Pheochromocytomas and Paragangliomas: Prospects for Future Therapies
  57. Association between TNM staging system and histopathological features in patients with papillary thyroid carcinoma
  58. Evaluation of bone markers in hypophosphatemic rickets/osteomalacia
  59. Association of the TGrI29 microsatellite in thyroglobulin gene with autoimmune thyroiditis in a Argentinian population: a case–control study
  60. Advances in TRH signaling
  61. Molecular backgrounds of age-related osteoporosis from mouse genetics approaches
  62. Quality of life, social situation, and sexual satisfaction, in adult males with congenital adrenal hyperplasia
  63. Quality of life, social situation, and sexual satisfaction, in adult males with congenital adrenal hyperplasia
  64. Safety and efficacy of a multiphase dietetic protocol with meal replacements including a step with very low calorie diet
  65. Solitary Fibrous Tumor of the Adrenal Gland with Unusual Immunophenotype: A Potential Diagnostic Problem and a Brief Review of Endocrine Organ Solitary Fibrous Tumor
  66. Disappearing adrenal masses
  67. Saturated free fatty acids: islet β cell “stressERs”
  68. Diet-induced obesity and prenatal undernutrition lead to differential neuroendocrine gene expression in the hypothalamic arcuate nuclei
  69. USP10 Expression in Normal Adrenal Gland and Various Adrenal Tumors
  70. The combination of TP53INP1, TP53INP2 and AXIN2: potential biomarkers in papillary thyroid carcinoma
  71. Immunohistochemical Study for IgG4-positive Plasmacytes in Pituitary Inflammatory Lesions
  72. Twenty years of gastroenteropancreatic neuroendocrine tumors: is reclassification worthwhile and feasible?
  73. Relationships between C-reactive protein, white blood cell count, and insulin resistance in a Chinese population
  74. Administration of human leptin differentially affects parameters of cortisol secretion in socially housed female rhesus monkeys
  75. Gangrene from finger pricking
Search Result: