Authors: Snary David
Publish Date: 1983/01/01
Volume: 77, Issue: 1, Pages: 126-129
Abstract
David Snary Cell surface glycoproteins of Trypanosoma cruzi protective immunity in mice and antibody levels in human chagasic sera Transactions of The Royal Society of Tropical Medicine and Hygiene Volume 77 Issue 1 1983 Pages 126–129 https//doiorg/101016/0035920383900378Two cell surface glycoproteins from Trypanosoma cruzi have been compared for their ability to protect mice against an acute lethal infection One of these a 90000 glycoprotein found on all stages of the parasite protected against both bloodstream and metacyclic trypomastigote challenge A 72000 glycoprotein found only on insectderived stages of T cruzi protected only against a metacyclic trypomastigote challenge Antibody against both of these glycoproteins was present in human chagasic sera
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