Authors: Antezana G Zeballos R Mendoza C Lyevre P Valda L Cardenas F Noriega I Ugarte H Dedet JP
Publish Date: 1992/01/01
Volume: 86, Issue: 1, Pages: 31-33
Abstract
G Antezana R Zeballos C Mendoza P Lyevre L Valda F Cardenas I Noriega H Ugarte JP Dedet Electrocardiographic alterations during treatment of mucocutaneous leishmaniasis with meglumine antimoniate and allopurinol Transactions of The Royal Society of Tropical Medicine and Hygiene Volume 86 Issue 1 JanuaryFebruary 1992 Pages 31–33 https//doiorg/101016/003592039290427EThe electrocardiographic ECG changes in Bolivian patients with mucocutaneous leishmaniasis treated with meglumine antimoniate and allopurinol were evaluated Electric changes due to the antimonial compound appeared in 45 of the patients and consisted of repolarization alteration principally affecting the T wave and the ST segment The changes disappeared within 2 months following the end of the antimonial treatment In patients with associated Chagas disease and leishmaniasis antimonial therapy did not aggravate the ECG changes characteristic of Chagasic cardiopathy
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