Authors: McGregor Ian Sturrock RF Otieno M James ER Webbe G
Publish Date: 1985/01/01
Volume: 79, Issue: 1, Pages: 129-131
Abstract
Ian McGregor RF Sturrock M Otieno ER James G Webbe A note on the efficacy of a new class of compounds 9acridanonehydrazones against Schistosoma mansoni in a primate—the baboon Transactions of The Royal Society of Tropical Medicine and Hygiene Volume 79 Issue 1 1985 Pages 129–131 https//doiorg/101016/0035920385902561Five 9acridanonehydrazone compounds were tested against moderately heavy Schistosoma mansoni infections in baboons They were administered as a single oral dose at a rate of 50 mg/kg bodyweight Compared with results from an untreated control baboon four of the compounds showed high levels of activity judged by the reduction or elimination of faecal egg production adult worms and tissue eggs
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