Authors: DK Hwang HJ Choi
Publish Date: 2009/06/30
Volume: 21, Issue: 3, Pages: 425-431
Abstract
We examined the relationship between low bond mass and metabolic syndrome in 2475 Korean women After adjustment for all covariates mean vertebral BMD was significantly lower in women with metabolic syndrome Moreover age and weight adjusted vertebral BMD was significantly decreased with additional components of the metabolic syndromeObesityinduced chronic inflammation is a key component in the pathogenesis of insulin resistance and metabolic syndrome It has been suggested that proinflammatory cytokines and lowgrade systemic inflammation activate bone resorption and may lead to reduced bone mineral density BMD The objective of this study was to determine the relationship between low bone mass and metabolic syndrome in Korean womenThis is a crosssectional study of 2548 women aged 18 years and over who had visited the Health Promotion Center Physical examination and laboratory tests were performed Vertebral BMD was measured using dualenergy Xray absorptiometry Metabolic syndrome was defined by National Cholesterol Education Program—Adult Treatment Panel III criteriaAmong 2475 women 511 210 women had metabolic syndrome Women with abdominal obesity or hypertriglyceridemia had significantly lower vertebral BMD than women without respective components after adjustment for age weight and height After adjustment for all covariates mean vertebral BMD was significantly lower in women with metabolic syndrome p = 0031 Moreover age and weightadjusted vertebral BMD were significantly decreased with additional components of the metabolic syndrome p = 0004
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