Authors: H Lv P Yin A Long Y Gao Z Zhao J Li L Zhang L Zhang P Tang
Publish Date: 2016/05/30
Volume: 27, Issue: 10, Pages: 3001-3009
Abstract
In this study we attempt to determine the clinical characteristic and risk factors of postoperative pneumonia POP after hip fracture surgery in a welldefined hip fracture cohort We find that intrinsic factors as well as major clinical interventions were all important risk factors of POPPostoperative pneumonia POP is one of the major complications following hip fractures surgery However the risk factors of POP are not well studied in hip fracture cohorts We attempt to determine the clinical characteristic and risk factors of POP after hip fracture surgery in a welldefined hip fracture cohortDatasets from a prospective hip fracture cohort study with a 2year followup period from 2000 to 2011 were reanalyzed for characteristics of POP Multivariate Cox proportional regression was used to evaluate the association between the incidence of POP and allcause mortality Multivariate logistic regression was used to screen for potential risk factors of POP by analyzing demographic factors comorbidities major clinical interventions and hematological parametersIn 1429 patients who underwent hip surgery the incidence of POP was 49 n = 70 Allcause mortality of patients with POP was significantly higher than that of patients without POP at 30 days hazard ratio HR 305 95 confidence intervals CI 188–494 1 year HR 187 95 CI 141–248 and 2 years HR 157 95 CI 123–199 postoperatively Multivariate logistic regression showed that intrinsic factors advanced age anemia diabetes prior stroke number of comorbidities ASA score ≥III and some laboratory biomarkers as well as major clinical interventions were all significant risk factors for POP
Keywords: