Authors: F S Neves L S A F Oliveira M G G Torres M B P Toralles M C B O da Silva M I G Campos P S F Campos I CrusoéRebello
Publish Date: 2011/10/18
Volume: 23, Issue: 7, Pages: 2037-2042
Abstract
In sickle cell disease erythroid hyperplasia causes trabecular destruction leading to low bone density This condition could be suspected by the radiomorphometric indices and your diagnosis becomes relevant in a multidisciplinary context of health care for sickle cell subjects providing prognostics and contributing to determine adequate therapeutic and preventive actionsSeventyeight Brazilian subjects with SCD took part in this study and were subdivided into four groups I 31 SCD subjects aged under 40 years II 13 SCD subjects aged 40 years or more III 12 normal subjects aged under 40 years and IV 22 normal subjects aged 40 years or more In the panoramic radiographs the mandibular cortical index MCI classification increased spacing of the trabecular bone panoramic mandibular index PMI and mental index MI were evaluated Exact Fishers test was used to compare age between the different groups Descriptive analysis of the data was performed to evaluate the simple visual estimation of low bone density increased bone trabecular space and MCI and a oneway analysis of variance Bonferroni criteria was used to compare the means of the quantitative indices PMI and MI The significance level was p 005In the MCI classification C2 was more prevalent especially in groups I and IV Increased spacing of the trabecular bone was more frequent in groups I and II MI did not show a statistically significant difference among the groups PMI showed a statistically significant difference only between groups III and IV
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