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Title of Journal: Osteoporos Int

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Abbravation: Osteoporosis International

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Publisher

Springer London

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DOI

10.1007/bf00642383

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ISSN

1433-2965

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Vitamin D status in men with psoriatic arthritis

Authors: Z Petho E KulcsarJakab E Kalina A Balogh A Pusztai K Gulyas A Horvath Z Szekanecz H P Bhattoa
Publish Date: 2015/02/19
Volume: 26, Issue: 7, Pages: 1965-1970
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Abstract

We determined hypovitaminosis D prevalence in men with psoriatic arthritis This is a crosssectional analyst blinded age and sexmatched casecontrol study Men with psoriatic arthritis have significantly lower 25hydroxyvitamin D levels Men with psoriatic arthritis are at increased odds of suffering from hypovitaminosis DSkeletal manifestations as a result of abrupted bone metabolism may be predominant in psoriatic arthritis PsA Vitamin D plays a vital role in maintenance of skeletal health and is known to modulate the immune system in various autoimmune diseases including PsA The aim of the present study was to determine the prevalence of hypovitaminosis D in a treatment naïve de novo psoriatic arthritis male cohort in a crosssectional analyst blinded age and sexmatched casecontrol studyThe prevalence of hypovitaminosis D 25 hydroxyvitamin D 25OHD levels 75 nmol/L was 81 and 57  in the PsA and control groups respectively Compared to the healthy controls 25OHD 672 12–137 nmol/L vs 519 15–95 nmol/L p = 0001 was significantly lower and osteocalcin 136 5–33 μg/L vs 182 6–35 μg/L p = 0003 and Cterminal telopeptides of typeI collagen 020 001–071 μg/L vs 028 006–069 μg/L p = 0008 were significantly higher in the PsA group A significant association was found between hypovitaminosis D and PsA the odds for patients with PsA of having hypovitaminosis D was 3297 95  confidence interval 1372 to 7922

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