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Title of Journal: Microchim Acta

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Abbravation: Microchimica Acta

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Springer Vienna

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DOI

10.1007/s13201-014-0217-3

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1436-5073

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Rapid determination of melamine in milk and milk p

Authors: Pinyi Ma Fanghui Liang Ying Sun Yue Jin Yang Chen Xinghua Wang Hanqi Zhang Dejiang Gao Daqian Song
Publish Date: 2013/07/17
Volume: 180, Issue: 11-12, Pages: 1173-1180
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Abstract

We have synthesized silver nanoparticles AgNPs decorated with αcyclodextrin CD by using the traditional silver mirror reaction in the presence of CD The CDAgNPs were used as substrate in surfaceenhanced Raman spectroscopy SERS for determining melamine The intensity of the Raman band of melamine at 704 cm−1 was used to determine melamine in milk and milk powder The use of CDAgNPs as the SERS substrate rather than classical silver nanoparticles makes the method more sensitive in giving an enhancement by a factor of up to ~ 106 in scattering efficiency The effects of the volume of solutions of CDAgNPs NaCl NaOH melamine and of mixing time were optimized The standard addition method was employed for quantitative analysis The correlation coefficient of the calibration plot is 09995 and the limit of detection is 30 μg L−1 The method was successfully applied to the determination of melamine in milk and milk powder with relative standard deviations of 10  and recoveries between 89 and 104 This work was supported by National “Twelfth FiveYear” Plan for Science and Technology Support No 2012BAF14B08 Program for New Century Excellent Talents in University No NECT100443 National Natural Science Foundation of China No 21105037 and Science and Technology Developing Foundation of Jilin Province No 20121808


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