Authors: Han Song Guipeng Xue Junjie Zhang Gang Wang BangCe Ye Shiguo Sun Liping Tian Yingchun Li
Publish Date: 2017/01/10
Volume: 184, Issue: 3, Pages: 843-853
Abstract
The authors describe an electrochemical sensor for simultaneous determination of dopamine DA and uric acid UA The sensor is based on the use of composite materials of carbonencapsulated hollow magnetite Fe3O4 nanoparticles and graphene oxide nanosheets which were homogeneously deposited on a glassy carbon electrode The morphology of the materials was characterized by transmission electron microscopy and scanning electron microscopy and the properties of differently decorated electrodes were investigated via cyclic voltammetry and differential pulse voltammetry DPV Simultaneous detection of DA and UA was carried out via DPV and the potentials of electrooxidation peaks are 014 V and 027 V vs SCE for DA and UA respectively The calibration plot is linear from 01 to 150 μM for DA and from 10 to 100 μM for UA with detection limits of 0053 μM and 041 μM at an S/N ratio of 3 The method was applied to the quantification of DA and UA in brain tissue urine and whole bloodSchematic of an electrochemical sensor for simultaneous voltammetric determination of dopamine DA and uric acid UA using 3D carbonencapsulated hollow Fe3O4 nanoparticles HFe3O4C anchored on graphene nanosheet GNS modified glassy carbon electrode GCEThe project financially supported by the Major Program for Science and Technology Development of Shihezi University gxjs2014zdgg04 National Natural Science Foundation of China 81260487 81460543 21575089 the Scientific Research Foundation for the Returned Overseas Chinese Scholars from Ministry of Human Resources and Social Security of China RSLX201301 the Pairing Program of Shihezi University with Eminent Scholar in Elite University SDJDZ201502 open Funding Project of the State Key Laboratory of Bioreactor Engineering and 2015 Key Technical Innovation Project of Xinjiang Uygur Autonomous Region
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