NAASLR and ICPAES Application in the Assessment

Authors: Vladimir Zaichick Sofia Zaichick

Publish Date: 2013/09/26

Volume: 156, Issue: 1-3, Pages: 357-366

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Abstract

The effect of age on the mass fraction of 19 chemical elements in the intact prostate of 50 apparently healthy 0–30yearold males was investigated by neutron activation analysis with highresolution spectrometry of shortlived radionuclides and inductively coupled plasma atomic emission spectrometry Mean values M ± standard error of the mean for mass fraction in milligrams per kilogram on dry weight basis of chemical elements were as follows Al 77 ± 17 B 131 ± 029 Ba 40 ± 12 Br 377 ± 43 Ca 1536 ± 189 Cl 13414 ± 949 Cu 123 ± 21 Fe 132 ± 11 K 11547 ± 468 Li 0064 ± 0009 Mg 922 ± 89 Mn 188 ± 016 Na 9834 ± 411 P 6741 ± 335 S 8034 ± 251 Si 199 ± 34 Sr 140 ± 019 and Zn 277 ± 33 The upper limit of mean mass fraction of V was ≤024 This work revealed that there is significant tendency for the mass fractions of Ca K Mg and Zn in the prostate tissue of healthy individuals to increase with age from the time of birth up to 30 years It means that Ca K Mg and Zn mass fractions in prostate tissue are the androgendependent parameters Our finding of a positive correlation between the prostatic Zn and Ca K Mg P and S mass fractions indicates that there is a special relationship of Zn with some main electrolytes Ca K and Mg and with P and Scontaining compounds in the prostate It was shown also that high levels of Al B Ba Br Cl Li Na and Sr mass fraction in prostate tissue do not indicate a direct involvement of these elements in the reproductive function of the prostateThe authors are grateful to the late Prof AA Zhavoronkov Institute of Human Morphology Russian Academy of Medical Sciences Moscow for supplying prostate specimens We are also grateful to Dr Karandaschev V Dr Nosenko S and Moskvina I Institute of Microelectronics Technology and High Purity Materials Chernogolovka Russia for their help in ICPAES analysis

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