Dietary Manganese Supplementation Influences the E

Authors: Shiping Bai Lirong Huang Yuheng Luo Leilei Wang Xuemei Ding Jianping Wang Qiufeng Zeng Keying Zhang

Publish Date: 2014/07/19

Volume: 160, Issue: 3, Pages: 352-360

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Abstract

To investigate the effects of dietary manganese Mn supplementation on iron Fe metabolism a total of 480 50weekold hens were fed the basal diet control 2435 mg Mn/kg without Mn supplementation for 6 weeks to reduce Mn storage in the body Hens were then randomly assigned to one of three treatments which included the control and control added with 60 or 300 mg Mn/kg diet MMn or HMn Duodenum heart liver and tibia were collected in hens after 12week feeding period No significant differences were observed in egg production feed/egg ratio shell breaking strength and shell thickness among different treatments Compared with control or MMn HMn decreased P  005 serum Fe concentration while increased P  005 total Febinding capacity TIBC The Fe concentration decreased P  005 in duodenum and tended to reduce P  010 in liver from control to MMn and to HMn whereas dietary Mn supplementation did not influence P  010 Fe concentration in the heart and tibia In conjunction with reduced Fe retention DMT1 mRNA expression decreased P  005 with dietary Mn concentration increasing in the duodenum and liver Duodenal FPN1 mRNA level was higher P  005 in HMn group than that in control or MMn group while hepatic FPN1 mRNA expression was lower P  005 in MMn or HMn group when compared with control The results demonstrated that dietary Mn supplementation decreased Fe concentration in duodenum and liver of hens which may be related to the alteration of DMT1 and FPN1 expression in these tissuesFinancial support was provided by the National Natural Science Foundation of China no 31001018 Specific Research Team Supporting Program of Sichuan Agricultural University Laying Hens Industry Chain Program of Sichuan Province 2011NZ0073 and 2014NZ0002 and Safety Production Technology Integration and Demonstration of Livestock and Poultry Products 2014BAD13B04 The authors thank Brittany Rice from Life and Agricultural Science College Virginia Polytechnic Institute and State University Blacksburg USA for valuable discussion and critical review

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