Effects of Cr Methionine on Glucose Metabolism Pl

Authors: A Emami M Ganjkhanlou A Zali

Publish Date: 2014/12/06

Volume: 164, Issue: 1, Pages: 50-57

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Abstract

This study was designed to investigate the effects of chromium methionine Cr–Met on glucose metabolism blood metabolites meat lipid peroxidation and tissue chromium Cr in Mahabadi goat kids Thirtytwo male kids 165 ± 28 kg BW 4–5 months of age were fed for 90 days in a completely randomized design with four treatments Treatments were supplemented with 0 control 05 1 and 15 mg Cr as Cr–Met/animal/daily Blood samples were collected via heparin tubes from the jugular vein on 0 21 42 63 and 90 days of experiment On day 70 an intravenous glucose tolerance test IVGTT was conducted At the end of the feeding trial the kids were slaughtered and the liver kidney and longissimus dorsi LD muscle samples were collected Plasma glucose insulin and triglyceride concentrations were decreased by Cr supplementation P  005 LD muscle malondialdehyde MDA decreased and plasma and tissue Cr contents increased with increasing supplemental Cr levels P  005 Plasma glucose concentrations at 30 and 60 min after glucose infusion were lower in the kids fed 15 mg Cr diet than the kids fed control diet P  005 The IVGTT indicated that the kids supplemented with 15 mg Cr had higher glucose clearance rate K and lower glucose halflife T½ P  005 Glucose area under the response curve AUC from 0 to 180 min after glucose infusion was decreased linearly P  001 by supplemental Cr The results suggested that supplemental Cr may improve glucose utilization and lipid oxidation of meat in fattening kid

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