Authors: Parissa Tabrizian Manijeh Moezzi Tehillah S Menes
Publish Date: 2010/07/03
Volume: 18, Issue: 4, Pages: 314-318
Abstract
The management of multiple synchronous groups of benignappearing calcifications in patients with a diagnosis of breast cancer or a highrisk lesion requiring excision is unclear The purpose of this study was to examine the results of biopsies of synchronous benignappearing microcalcifications in patients with a concurrent abnormal pathology result requiring surgeryA review was performed of all breast stereotacticguided vacuum biopsies done at Elmhurst Hospital Center Elmhurst NY USA between January 2006 and February 2009 Patients with an abnormal pathology result that had further biopsies of synchronous benign or probably benign microcalcifications were includedTwo hundred and fiftytwo patients had abnormal biopsy results Twentyeight patients with additional clusters of microcalcifications reported as benign or probably benign underwent 34 additional biopsies Abnormal pathology results were found in half of these biopsies changing the surgical plan in 14 patients In patients with ductal carcinoma in situ DCIS this rate was 71 Four patients had their diagnosis upgradedIn patients with abnormal findings on stereotactic biopsy of microcalcifications synchronous benignappearing microcalcifications are associated with a high rate of abnormal pathology A ‘second look’ at the mammogram and further biopsy of other clusters of benignappearing microcalcifications should be considered in patients with DCIS who are planning to undergo breastconserving treatment
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