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Title of Journal: Parasitol Res

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Abbravation: Parasitology Research

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Springer-Verlag

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DOI

10.1007/978-3-319-03107-1_18

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1432-1955

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Chemotherapy in alveolar echinococcosis of multio

Authors: Haitao Li Tao Song Yingmei Shao Aili Tuergan Bo Ran Hao Wen
Publish Date: 2013/03/19
Volume: 112, Issue: 6, Pages: 2237-2243
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Abstract

The aim of this study was to investigate the clinical efficiency of chemotherapy for the treatment of human alveolar echinococcosis AE Twentyfour patients who suffered from latestage AE were enrolled in this study The classification of the disease stages was performed according to the PNM parasite lesion neighboring organ invasion metastases classification system established by the World Health Organization Informal Working Group on Echinococcosis and classification standards Radical surgery n = 3 palliative surgery plus chemotherapy n = 11 and sole chemotherapy n = 10 were given respectively For those with AE metastasis with spleen and kidney radical surgery was effective for the treatment However the treatment efficiency for those with AE metastasis to bone tissues was unfavorable Significant improvement was noted in those with cerebral lesions after chemotherapy Stable health conditions were observed in those with pulmonary lesions after chemotherapy For those with liver lesion long stable health conditions were noted after chemotherapy However surgical interventions were needed as the occurrence of bile duct complications With regards to the other lesions radical surgeries were recommended Satisfactory treatment outcomes were obtained in those with AE after chemotherapyWe are very grateful to Professor Dominique Angele Vuitton University of FrancheComt for her valuable help in revising all draft versions and the definitive version of the manuscript constructive advice and comments on this study We thank the anonymous reviewers for the reviewing of this manuscript This work was supported by the Xinjiang KeyLab project grants on Echinococcosis grant no XJDX0202201104

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